MTFR2

Entrez Summary: N/A
UniProt Summary: May play a role in mitochondrial aerobic respiration essentially in the testis. Can also promote mitochondrial fission (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Nicotinamide 2000μM R01 exp50	-2.37
Combretastatin A4 0.002 to 0.003μM day4 R04 exp179	1.7
Vincristine 0.0005μM R04 exp190	1.96
Caffeine 2600μM R08 exp463	1.98

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

mitochondrial fission
aerobic respiration
cellular respiration
energy derivation by oxidation of organic compounds
organelle fission
generation of precursor metabolites and energy
mitochondrion organization
oxidation-reduction process
mitochondrion