OTOR

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Pomalidomide 20μM R07 exp391	-2.05
BI-D1870 2μM R04 exp162	-1.95
IL-3 9ng/ml R08 exp493	-1.85
All-trans-Retinoic-Acid 40μM R07 exp334	-1.82
Rapamycin 2μM plus FK-506 5μM R07 exp308	1.75

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

cartilage condensation
cell aggregation
sensory perception of sound
sensory perception of mechanical stimulus
cartilage development
connective tissue development
skeletal system morphogenesis
skeletal system development
animal organ morphogenesis
sensory perception
nervous system process
tissue development
extracellular region
system process