R3HCC1 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: R3HCC1
Official Name: R3H domain and coiled-coil containing 1
Aliases and Previous Symbols: N/A
Entrez ID: 203069
UniProt: Q9Y3T6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Dihydrosphingosine 8μM R08 exp476	-2.27
Prochlorperazine 5.2μM R02 exp77	-2.06
L-BMAA 500 to 750μM on day4 R04 exp185	-1.98
GSK-LSD1 10μM R03 exp123	-1.97
Hinokiflavone 12μM R08 exp487	-1.86
Alpha-Amanitin 0.5μM R00 exp5	-1.83
Lead acetate 2000μM R08 exp497	-1.79
RS-1 10μM R08 exp519	-1.71
ABT-702 5μM R07 exp318	1.7
Cytochalasin-B 5μM R07 exp349	1.72
Lapatinib 5μM R01 exp47	1.74
Taxol 0.002μM R01 exp54	1.76
UMK57 1μM R01 exp59	1.83

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 6489
Expression level (log2 read counts): 4.27

Expression Distribution

Last modified: 2026/01/07 22:36
by 127.0.0.1