RNPS1
Gene Information
- Official Symbol: RNPS1
- Official Name: RNA binding protein with serine rich domain 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 10921
- UniProt: Q15287
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| RRM 1 |
GO Terms
| ASAP complex |
| negative regulation of mRNA splicing, via spliceosome |
| exon-exon junction complex |
| negative regulation of RNA splicing |
| negative regulation of mRNA processing |
| regulation of alternative mRNA splicing, via spliceosome |
| mRNA 3-UTR binding |
| negative regulation of mRNA metabolic process |
| mRNA 3-end processing |
| regulation of mRNA splicing, via spliceosome |
| mRNA-containing ribonucleoprotein complex export from nucleus |
| mRNA export from nucleus |
| nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| ribonucleoprotein complex export from nucleus |
| ribonucleoprotein complex localization |
| RNA export from nucleus |
| RNA 3-end processing |
| regulation of RNA splicing |
| regulation of mRNA processing |
| protein export from nucleus |
| mRNA transport |
| nuclear export |
| RNA transport |
| nucleic acid transport |
| establishment of RNA localization |
| nuclear-transcribed mRNA catabolic process |
| RNA localization |
| mRNA catabolic process |
| nucleobase-containing compound transport |
| RNA catabolic process |
| protein-containing complex localization |
| nucleocytoplasmic transport |
| nuclear transport |
| mRNA splicing, via spliceosome |
| RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| RNA splicing, via transesterification reactions |
| regulation of mRNA metabolic process |
| nucleobase-containing compound catabolic process |
| RNA splicing |
| nuclear speck |
| heterocycle catabolic process |
| cellular nitrogen compound catabolic process |
| aromatic compound catabolic process |
| mRNA processing |
| organic cyclic compound catabolic process |
| transcription, DNA-templated |
| nucleic acid-templated transcription |
| positive regulation of apoptotic process |
| positive regulation of programmed cell death |
| RNA biosynthetic process |
| mRNA metabolic process |
| positive regulation of cell death |
| RNA processing |
| cellular macromolecule catabolic process |
| intracellular protein transport |
| macromolecule catabolic process |
| nucleobase-containing compound biosynthetic process |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| organic cyclic compound biosynthetic process |
| negative regulation of RNA metabolic process |
| RNA binding |
| negative regulation of nucleobase-containing compound metabolic process |
| protein transport |
| intracellular transport |
| peptide transport |
| regulation of apoptotic process |
| regulation of programmed cell death |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| cellular nitrogen compound biosynthetic process |
| RNA metabolic process |
| regulation of cell death |
| cellular macromolecule biosynthetic process |
| negative regulation of gene expression |
| macromolecule biosynthetic process |
| organic substance catabolic process |
| cellular catabolic process |
| establishment of localization in cell |
| nitrogen compound transport |
| gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 370/726
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 1/1 |
| bile duct | 17/28 |
| blood | 17/28 |
| bone | 16/25 |
| breast | 20/33 |
| central nervous system | 30/56 |
| cervix | 0/4 |
| colorectal | 8/17 |
| esophagus | 6/13 |
| fibroblast | 1/1 |
| gastric | 7/15 |
| kidney | 9/21 |
| liver | 13/20 |
| lung | 37/75 |
| lymphocyte | 6/14 |
| ovary | 15/26 |
| pancreas | 13/24 |
| peripheral nervous system | 12/16 |
| plasma cell | 5/15 |
| prostate | 1/1 |
| skin | 16/24 |
| soft tissue | 3/7 |
| thyroid | 1/2 |
| upper aerodigestive | 4/22 |
| urinary tract | 10/29 |
| uterus | 2/5 |
Essentiality in NALM6
- Essentiality Rank: 3395
- Expression level (log2 read counts): 7.58
Expression Distribution
RNPS1 Expression in NALM6 Cells: 7.58
