TNRC18 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: TNRC18
Official Name: trinucleotide repeat containing 18
Aliases and Previous Symbols: N/A
Entrez ID: 84629
UniProt: O15417
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
BML-284 0.09μM R08 exp460	-1.73
R-DABN 8μM R03 exp111	1.8
BI-6727 0.04μM R03 exp98	1.87
HMS-I1 10μM R06 exp256	2.16
DABN racemic mixture R03 exp93	2.78
Nocodazole 0.2μM R00 exp24	2.78
Nocodazole 0.1μM R03 exp94	3.21
Nocodazole 0.2μM R02 exp64	3.31
Vinblastine 0.015μM R05 exp208	3.37
Rotenone 2μM R00 exp33	3.73
SB743921 0.001μM R05 exp244	4.15

Global Fraction of Cell Lines Where Essential: 2/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 9748
Expression level (log2 read counts): 6.62

Expression Distribution

Last modified: 2026/01/07 22:37
by 127.0.0.1