TP53I13

Entrez Summary: N/A
UniProt Summary: May act as a tumor suppressor. Inhibits tumor cell growth, when overexpressed. {ECO:0000269|PubMed:14767535}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Cycloheximide 0.2μM R00 exp15	-2.03
Oligomycin-A 2μM R00 exp25	-1.97
Nocodazole 0.2μM R02 exp64	-1.92
Doxorubicin 0.02μM R08 exp478	-1.71
Calcipotriol 5μM R08 exp464	1.89
Trientine 500μM R08 exp534	1.94
Rapamycin 2μM plus Cyclosporin-A 3μM R07 exp307	2.12
Senexin-A 25μM R07 exp400	2.13
UM0011500 5μM R05 exp245	2.81

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

response to UV
response to light stimulus
response to radiation
negative regulation of cell cycle
molecular function
response to organic cyclic compound
response to drug
response to abiotic stimulus
regulation of cell cycle