USE1

Entrez Summary: N/A
UniProt Summary: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. {ECO:0000269|PubMed:15272311}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 10/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	1/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	2/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	2/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	1/29
uterus	0/5

Expression Distribution

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
lysosomal transport
vacuolar transport
endoplasmic reticulum to Golgi vesicle-mediated transport
lysosome
Golgi vesicle transport
protein catabolic process
endoplasmic reticulum membrane
secretion by cell
endoplasmic reticulum
export from cell
macromolecule catabolic process
organonitrogen compound catabolic process
secretion
protein transport
intracellular transport
peptide transport
amide transport
establishment of protein localization
organic substance catabolic process
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport