USP42

Entrez Summary: N/A
UniProt Summary: Deubiquitinating enzyme which may play an important role during spermatogenesis. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

thiol-dependent ubiquitinyl hydrolase activity
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein deubiquitination
protein modification by small protein removal
ubiquitin-dependent protein catabolic process
modification-dependent protein catabolic process
modification-dependent macromolecule catabolic process
spermatogenesis
male gamete generation
proteolysis involved in cellular protein catabolic process
cellular protein catabolic process
protein catabolic process
gamete generation
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
cellular macromolecule catabolic process
protein modification by small protein conjugation or removal
multi-organism reproductive process
macromolecule catabolic process
organonitrogen compound catabolic process
proteolysis
reproductive process
reproduction
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
organic substance catabolic process
cellular catabolic process