ZBED4

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Chloroquine 32μM R08 exp470	-2.33
BML-284 0.09μM R08 exp460	-2.06
Colchicine 0.009μM R05 exp215	-2.01
IU1-47 25μM R04 exp182	-1.92
Dihydrosphingosine 8μM R08 exp476	-1.87
TIC10 10μM R08 exp532	-1.8
JQ1 0.8μM R08 exp435	-1.73
All-trans-Retinoic-Acid 8μM R07 exp333	1.7
MK-1775 0.32μM R02 exp75	1.73
Ethambutol 25μM R08 exp481	1.93

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Dimer Tnp hAT
zf-BED

protein dimerization activity
DNA binding
DNA-binding transcription factor activity, RNA polymerase II-specific