Pfam Domains GO Terms
| Acyltransferase |
| CDP-diacylglycerol biosynthetic process |
| CDP-diacylglycerol metabolic process |
| 1-acylglycerol-3-phosphate O-acyltransferase activity |
| phosphatidic acid biosynthetic process |
| phosphatidic acid metabolic process |
| pyrimidine nucleotide biosynthetic process |
| positive regulation of cytokine-mediated signaling pathway |
| pyrimidine-containing compound biosynthetic process |
| positive regulation of response to cytokine stimulus |
| pyrimidine nucleotide metabolic process |
| pyrimidine-containing compound metabolic process |
| regulation of cytokine-mediated signaling pathway |
| regulation of response to cytokine stimulus |
| glycerophospholipid biosynthetic process |
| glycerolipid biosynthetic process |
| nucleotide biosynthetic process |
| phospholipid biosynthetic process |
| nucleoside phosphate biosynthetic process |
| glycerophospholipid metabolic process |
| phospholipid metabolic process |
| glycerolipid metabolic process |
| nucleotide metabolic process |
| positive regulation of cytokine production |
| nucleoside phosphate metabolic process |
| organophosphate biosynthetic process |
| nucleobase-containing small molecule metabolic process |
| lipid biosynthetic process |
| regulation of cytokine production |
| organophosphate metabolic process |
| endoplasmic reticulum membrane |
| cellular lipid metabolic process |
| endoplasmic reticulum |
| nucleobase-containing compound biosynthetic process |
| heterocycle biosynthetic process |
| aromatic compound biosynthetic process |
| lipid metabolic process |
| organic cyclic compound biosynthetic process |
| organonitrogen compound biosynthetic process |
| cellular nitrogen compound biosynthetic process |
| positive regulation of signal transduction |
| positive regulation of multicellular organismal process |
| small molecule metabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| membrane |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 2/75 |
| lymphocyte | 2/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution