PPP6R3

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
LB-100 2μM R05 exp210	-1.95
Epigallocatechin gallate 20μM R05 exp230	-1.76
Selumetinib 20μM R02 exp81	-1.72
LY2090314 0.003μM R08 exp500 no dilution day6	1.71
LY2090314 0.003μM R08 exp499	1.79
Sulforaphane 9μM R08 exp525	1.8
Cannabidiol 20μM R08 exp466	1.82
Tubacin 1.6μM R07 exp416	1.92
Sulforaphane 9μM R08 exp526 no dilution day6	1.97
UM131593 0.2μM R03 exp106	2
CCT251545 0.2μM R06 exp271	2.09
Mdivi-1 15μM R05 exp217	2.18
UMK57 1μM R01 exp59	3.05
Quercetin 20μM R08 exp517	3.07
BML-284 0.09μM R08 exp460	3.12
RO-3307 4.7μM R02 exp80	3.65

Global Fraction of Cell Lines Where Essential: 11/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	2/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	1/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	1/15
prostate	0/1
skin	3/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	1/29
uterus	1/5

Expression Distribution