GTSE1
Gene Information
- Official Symbol: GTSE1
- Official Name: G2 and S-phase expressed 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 51512
- UniProt: Q9NYZ3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| positive regulation of protein export from nucleus |
| regulation of protein export from nucleus |
| cytoplasmic microtubule |
| DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest |
| intracellular signal transduction involved in G1 DNA damage checkpoint |
| signal transduction involved in mitotic DNA integrity checkpoint |
| signal transduction involved in mitotic G1 DNA damage checkpoint |
| signal transduction involved in mitotic cell cycle checkpoint |
| signal transduction involved in mitotic DNA damage checkpoint |
| mitotic G1 DNA damage checkpoint |
| positive regulation of nucleocytoplasmic transport |
| mitotic G1/S transition checkpoint |
| G1 DNA damage checkpoint |
| signal transduction involved in DNA damage checkpoint |
| signal transduction involved in DNA integrity checkpoint |
| signal transduction involved in cell cycle checkpoint |
| positive regulation of protein localization to nucleus |
| DNA damage response, signal transduction by p53 class mediator |
| positive regulation of cell cycle arrest |
| mitotic DNA damage checkpoint |
| negative regulation of G1/S transition of mitotic cell cycle |
| mitotic DNA integrity checkpoint |
| signal transduction in response to DNA damage |
| regulation of nucleocytoplasmic transport |
| negative regulation of cell cycle G1/S phase transition |
| regulation of cell cycle arrest |
| regulation of protein localization to nucleus |
| signal transduction by p53 class mediator |
| DNA damage checkpoint |
| DNA integrity checkpoint |
| regulation of G1/S transition of mitotic cell cycle |
| mitotic cell cycle checkpoint |
| positive regulation of intracellular protein transport |
| regulation of cell cycle G1/S phase transition |
| protein stabilization |
| cell cycle checkpoint |
| positive regulation of intracellular transport |
| regulation of cell cycle G2/M phase transition |
| negative regulation of mitotic cell cycle phase transition |
| regulation of intracellular protein transport |
| negative regulation of cell cycle phase transition |
| positive regulation of cell cycle process |
| regulation of protein stability |
| negative regulation of mitotic cell cycle |
| positive regulation of cellular protein localization |
| negative regulation of cell cycle process |
| regulation of intracellular transport |
| positive regulation of cell cycle |
| regulation of mitotic cell cycle phase transition |
| positive regulation of protein transport |
| regulation of cell cycle phase transition |
| positive regulation of establishment of protein localization |
| positive regulation of cell migration |
| positive regulation of cell motility |
| positive regulation of cellular component movement |
| regulation of cellular protein localization |
| positive regulation of locomotion |
| negative regulation of cell cycle |
| mitotic cell cycle process |
| regulation of mitotic cell cycle |
| microtubule-based process |
| mitotic cell cycle |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| regulation of cell cycle process |
| molecular function |
| cellular response to DNA damage stimulus |
| regulation of cell migration |
| regulation of cell motility |
| regulation of cellular localization |
| regulation of locomotion |
| positive regulation of transport |
| regulation of cellular component movement |
| cell cycle process |
| regulation of protein localization |
| regulation of cell cycle |
| cell cycle |
| intracellular signal transduction |
| cellular response to stress |
| regulation of transport |
| membrane |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 8/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 1/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 1/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 1/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 1/22 |
| urinary tract | 1/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 3877
- Expression level (log2 read counts): 6.82
Expression Distribution
GTSE1 Expression in NALM6 Cells: 6.82
