ITGB8

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

integrin alphav-beta8 complex
extracellular matrix protein binding
regulation of transforming growth factor beta activation
ganglioside metabolic process
cell adhesion mediated by integrin
integrin complex
placenta blood vessel development
regulation of transforming growth factor beta production
glycosphingolipid metabolic process
vasculogenesis
ceramide metabolic process
integrin-mediated signaling pathway
glycolipid metabolic process
liposaccharide metabolic process
cell-matrix adhesion
integrin binding
placenta development
sphingolipid metabolic process
positive regulation of angiogenesis
cartilage development
positive regulation of vasculature development
cell-substrate adhesion
membrane lipid metabolic process
signaling receptor activity
connective tissue development
regulation of angiogenesis
regulation of vasculature development
extracellular matrix organization
extracellular structure organization
blood vessel morphogenesis
focal adhesion
reproductive structure development
reproductive system development
blood vessel development
skeletal system development
vasculature development
cardiovascular system development
cell surface
tube morphogenesis
developmental process involved in reproduction