NCOA5

Gene Information
  • Official Symbol: NCOA5
  • Official Name: nuclear receptor coactivator 5
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 57727
  • UniProt: Q9HCD5
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC in response to 17-beta-estradiol (E2). {ECO:0000269|PubMed:15073177}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 6518
  • Expression level (log2 read counts): 6.01

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1