OR4M2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312	-1.96
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	-1.95
Citral 50μM R06 exp274	-1.92
HMS-I1 10μM R06 exp256	-1.89
Talazoparib 0.006μM R06 exp299	-1.88
Tozasertib 0.1μM R07 exp414	-1.71
∆-9-Tetrahydrocannabinol 30μM R08 exp445	1.78
ML-792 0.2μM R08 exp505	1.83
CyclicAMP 200μM R08 exp475	1.86
QNZ 0.01μM R05 exp241	1.86
ETC-159 50μM R08 exp480	1.87
ONC212 0.15μM R08 exp513	1.9
Vemurafenib 6.6μM R08 exp434	2.02
Bisphenol F 50μM R08 exp457	2.03
MS023 7μM R03 exp135	2.07
Bafilomycin-A1 0.009μM R08 exp454	2.19
Epothilone-B 0.0015μM R05 exp231	2.26

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

olfactory receptor activity
detection of chemical stimulus involved in sensory perception of smell
sensory perception of smell
detection of chemical stimulus involved in sensory perception
detection of chemical stimulus
sensory perception of chemical stimulus
detection of stimulus involved in sensory perception
detection of stimulus
G protein-coupled receptor activity
sensory perception
G protein-coupled receptor signaling pathway
nervous system process
system process