PPP1R12A

Gene Information
  • Official Symbol: PPP1R12A
  • Official Name: protein phosphatase 1 regulatory subunit 12A
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 4659
  • UniProt: O14974
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity. {ECO:0000269|PubMed:18477460, ECO:0000269|PubMed:19245366, ECO:0000269|PubMed:20354225}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1553
  • Expression level (log2 read counts): 6.89

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1