SFXN1

Entrez Summary: N/A
UniProt Summary: Might be involved in the transport of a component required for iron utilization into or out of the mitochondria.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Gene	Correlation
MTHFD1L	0.439
SLC25A32	0.429

D-serine transmembrane transporter activity
serine import into mitochondrion
D-serine transport
L-serine transport
L-serine transmembrane transporter activity
D-amino acid transport
serine transport
amino acid import
one-carbon metabolic process
integral component of mitochondrial inner membrane
neutral amino acid transport
L-amino acid transport
iron ion transport
amino acid transmembrane transport
erythrocyte differentiation
erythrocyte homeostasis
mitochondrial transmembrane transport
myeloid cell homeostasis
amino acid transport
transition metal ion transport
carboxylic acid transmembrane transport
organic acid transmembrane transport
drug transport
homeostasis of number of cells
mitochondrial transport
myeloid cell differentiation
anion transmembrane transport
organic acid transport
carboxylic acid transport
organic anion transport
hemopoiesis
anion transport
hematopoietic or lymphoid organ development
cation transmembrane transport
metal ion transport
immune system development
cation transport
ion transmembrane transport
response to drug
mitochondrion