UBR4

• Official Symbol: UBR4
• Official Name: ubiquitin protein ligase E3 component n-recognin 4
• Aliases and Previous Symbols: N/A
• Entrez ID: 23352
• UniProt: Q5T4S7
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein. [provided by RefSeq, Aug 2010].
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 1574
• Expression level (log2 read counts): 8.61

Expression Distribution

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UBR4 Expression in NALM6 Cells: 8.61