VN1R4

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Thioridazine 5μM R08 exp530	-2.1
Diepoxybutane 3μM R07 exp354	-2
Pyronaridine 1μM R06 exp295	-1.91
Epothilone-D 0.004 to 0.006μM on day4 R05 exp232	-1.86
GSK-J5 1.5μM R08 exp484	-1.8
S-trityl-L-cysteine 0.5μM R05 exp243	-1.8
Atovaquone 15μM R08 exp451	-1.78
GSK461364A 0.1μM R03 exp126	1.7
BI-2536 0.001μM R01 exp41	1.71
HMS-I1 1μM R01 exp46	1.82
Geldanamycin 0.015 to 0.025μM on day4 R07 exp316	1.9
Brefeldin A 0.02μM R00 exp8	1.96
Trimetrexate 0.03μM R08 exp535	2.27
Isonicotinamide 500μM R03 exp129	2.58

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

pheromone receptor activity
pheromone binding
response to pheromone
G protein-coupled receptor signaling pathway