ZBED2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
TIC10 10μM R08 exp532	-2.58
Epothilone-D 0.004 to 0.006μM on day4 R05 exp232	-2.25
Phorbol-12-myristate-13-acetate 0.57μM R08 exp514	-2.06
Rotenone 20μM R00 exp34	-1.95
D-Fructose 10000μM R06 exp279	-1.9
Azithromycin 100μM R08 exp452	-1.73
PU-H71 1μM R08 exp515	-1.71
Cadmium 60μM R08 exp462	-1.7
QNZ 0.01μM R05 exp241	1.82
Pomalidomide 20μM R07 exp391	1.94
BH1 1μM R04 exp169	1.99
KU-0063794 3.8μM R02 exp71	2.06
GSK-J4 1-1.25μM to day4 R07 exp363	2.1
Dihydrosphingosine 8μM R08 exp476	2.13

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of canonical Wnt signaling pathway
positive regulation of Wnt signaling pathway
regulation of canonical Wnt signaling pathway
regulation of Wnt signaling pathway
positive regulation of transcription by RNA polymerase II
DNA binding
positive regulation of transcription, DNA-templated
DNA-binding transcription factor activity, RNA polymerase II-specific
positive regulation of nucleic acid-templated transcription
positive regulation of RNA biosynthetic process
positive regulation of signal transduction
positive regulation of RNA metabolic process
positive regulation of cell communication
positive regulation of signaling
positive regulation of nucleobase-containing compound metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cellular biosynthetic process
positive regulation of gene expression
positive regulation of biosynthetic process