BTBD9

Entrez Summary: This locus encodes a BTB/POZ domain-containing protein. This domain is known to be involved in protein-protein interactions. Polymorphisms at this locus have been reported to be associated with susceptibility to Restless Legs Syndrome and may also be associated with Tourette Syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	1/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

circadian sleep/wake cycle, non-REM sleep
circadian sleep/wake cycle, sleep
circadian sleep/wake cycle process
circadian sleep/wake cycle
multicellular organismal iron ion homeostasis
serotonin metabolic process
primary amino compound metabolic process
sleep
regulation of synaptic vesicle endocytosis
sensory perception of temperature stimulus
circadian behavior
rhythmic behavior
indole-containing compound metabolic process
regulation of synaptic vesicle recycling
long-term memory
adult locomotory behavior
iron ion homeostasis
phenol-containing compound metabolic process
neurotransmitter metabolic process
regulation of synaptic vesicle cycle
memory
transition metal ion homeostasis
circadian rhythm
adult behavior
ammonium ion metabolic process
locomotory behavior
regulation of endocytosis
learning or memory
rhythmic process
cognition
multicellular organismal homeostasis
regulation of neurotransmitter levels
organic hydroxy compound metabolic process
regulation of vesicle-mediated transport
behavior
metal ion homeostasis
cation homeostasis
inorganic ion homeostasis
ion homeostasis
regulation of cellular localization