COG4
Gene Information
- Official Symbol: COG4
- Official Name: component of oligomeric golgi complex 4
- Aliases and Previous Symbols: N/A
- Entrez ID: 25839
- UniProt: Q9H9E3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010].
- UniProt Summary: Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. {ECO:0000269|PubMed:19536132}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 699
- Expression level (log2 read counts): 5.98