COG4

Gene Information
  • Official Symbol: COG4
  • Official Name: component of oligomeric golgi complex 4
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 25839
  • UniProt: Q9H9E3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010].
  • UniProt Summary: Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1. {ECO:0000269|PubMed:19536132}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 699
  • Expression level (log2 read counts): 5.98

Expression Distribution

  • Last modified: 2026/01/07 22:36
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