CPLX3

Entrez Summary: N/A
UniProt Summary: Positively regulates a late step in synaptic vesicle exocytosis. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

anchored component of presynaptic active zone membrane
photoreceptor ribbon synapse
neurotransmitter transmembrane transporter activity
regulation of synaptic vesicle fusion to presynaptic active zone membrane
anchored component of synaptic vesicle membrane
regulation of vesicle fusion
insulin secretion
SNARE complex
terminal bouton
syntaxin binding
peptide hormone secretion
synaptic vesicle exocytosis
SNARE binding
hormone secretion
regulation of synaptic vesicle exocytosis
hormone transport
neurotransmitter secretion
signal release from synapse
regulation of neurotransmitter secretion
regulation of synaptic vesicle cycle
synaptic vesicle cycle
vesicle-mediated transport in synapse
regulation of neurotransmitter transport
protein secretion
establishment of protein localization to extracellular region
regulation of regulated secretory pathway
protein localization to extracellular region
signal release
peptide secretion
neurotransmitter transport
visual perception
regulation of exocytosis
sensory perception of light stimulus
regulation of neurotransmitter levels
chemical synaptic transmission
anterograde trans-synaptic signaling
trans-synaptic signaling
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
synaptic signaling