ELMO1

Gene Information
  • Official Symbol: ELMO1
  • Official Name: engulfment and cell motility 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 9844
  • UniProt: Q92556
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. {ECO:0000269|PubMed:11595183, ECO:0000269|PubMed:12134158}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 10679
  • Expression level (log2 read counts): 5.79

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1