ENO2

Entrez Summary: N/A
UniProt Summary: Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Enolase N
Enolase C

phosphopyruvate hydratase complex
phosphopyruvate hydratase activity
glucose catabolic process to pyruvate
NADH regeneration
canonical glycolysis
glycolytic process through glucose-6-phosphate
glycolytic process through fructose-6-phosphate
glucose catabolic process
NADH metabolic process
glycolytic process
ATP generation from ADP
gluconeogenesis
NAD metabolic process
hexose biosynthetic process
photoreceptor inner segment
ADP metabolic process
hexose catabolic process
monosaccharide biosynthetic process
nucleoside diphosphate phosphorylation
nucleotide phosphorylation
monosaccharide catabolic process
purine ribonucleoside diphosphate metabolic process
purine nucleoside diphosphate metabolic process
ribonucleoside diphosphate metabolic process
pyruvate metabolic process
nucleoside diphosphate metabolic process
glucose metabolic process
carbohydrate catabolic process
carbohydrate biosynthetic process
perikaryon
hexose metabolic process
monosaccharide metabolic process
ATP metabolic process
magnesium ion binding
purine ribonucleotide metabolic process
ribonucleotide metabolic process
purine nucleotide metabolic process
ribose phosphate metabolic process
purine-containing compound metabolic process
generation of precursor metabolites and energy