EPC1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 8/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	1/28
blood	0/28
bone	0/25
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	1/15
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	1/14
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	2/15
prostate	0/1
skin	0/24
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

E Pc C
EPL1

Piccolo NuA4 histone acetyltransferase complex
vascular smooth muscle cell differentiation
histone H2A acetylation
NuA4 histone acetyltransferase complex
smooth muscle cell differentiation
negative regulation of G0 to G1 transition
regulation of G0 to G1 transition
histone acetyltransferase activity
histone H4 acetylation
negative regulation of gene expression, epigenetic
histone acetylation
internal peptidyl-lysine acetylation
peptidyl-lysine acetylation
internal protein amino acid acetylation
protein acetylation
protein acylation
regulation of gene expression, epigenetic
nuclear membrane
muscle cell differentiation
peptidyl-lysine modification
negative regulation of cell cycle process
histone modification
covalent chromatin modification
muscle structure development
vasculature development
cardiovascular system development
negative regulation of cell cycle
transcription, DNA-templated
nucleic acid-templated transcription
RNA biosynthetic process
regulation of growth
chromatin organization
regulation of cell cycle process
negative regulation of transcription by RNA polymerase II
circulatory system development
peptidyl-amino acid modification
chromosome organization
nucleobase-containing compound biosynthetic process
heterocycle biosynthetic process
aromatic compound biosynthetic process