GPR84
Gene Information
- Official Symbol: GPR84
- Official Name: G protein-coupled receptor 84
- Aliases and Previous Symbols: N/A
- Entrez ID: 53831
- UniProt: Q9NQS5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. {ECO:0000269|PubMed:16966319}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 3813
- Expression level (log2 read counts): -3.8