METAP1

Gene Information
  • Official Symbol: METAP1
  • Official Name: methionyl aminopeptidase 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 23173
  • UniProt: P53582
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Required for normal progression through the cell cycle. {ECO:0000255|HAMAP- Rule:MF_03174, ECO:0000269|PubMed:16274222, ECO:0000269|PubMed:17114291}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 4651
  • Expression level (log2 read counts): 6.52

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1