RADIL

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
HMS-I2 10μM R06 exp288	-1.91
Apcin 25μM plus proTAME 2μM R04 exp177	1.7
UM0130462 0.025 to 0.035μM day4 R05 exp247	1.7
UM0131023 0.05μM R05 exp248	1.74
Cholesterol 0.003 to 0.006 to 0.1μM on day2 then day6 R08 exp471	1.76
Nocodazole 0.2μM R00 exp24	1.76
HMS-I1 1μM R01 exp46	1.83
Rotenone 2μM R00 exp33	2.42
Nocodazole 0.1μM R03 exp94	2.48
DABN racemic mixture R03 exp93	2.81
HMS-I1 10μM R06 exp256	3
Vinblastine 0.015μM R05 exp208	3.26
SB743921 0.001μM R05 exp244	3.47

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

substrate adhesion-dependent cell spreading
cell-substrate adhesion
microtubule
cell morphogenesis involved in differentiation
protein-containing complex
cell morphogenesis
cellular component morphogenesis
cell adhesion
biological adhesion
cell development