RPL22
Gene Information
- Official Symbol: RPL22
- Official Name: ribosomal protein L22
- Aliases and Previous Symbols: N/A
- Entrez ID: 6146
- UniProt: P35268
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Ribosomal L22e |
GO Terms
| regulation of translation at presynapse |
| regulation of translation at presynapse, modulating synaptic transmission |
| regulation of translation at synapse |
| regulation of translation at synapse, modulating synaptic transmission |
| presynaptic modulation of chemical synaptic transmission |
| translation regulator activity |
| alpha-beta T cell differentiation |
| alpha-beta T cell activation |
| cytosolic large ribosomal subunit |
| presynapse |
| SRP-dependent cotranslational protein targeting to membrane |
| cotranslational protein targeting to membrane |
| protein targeting to ER |
| establishment of protein localization to endoplasmic reticulum |
| viral transcription |
| nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| viral gene expression |
| T cell differentiation |
| protein localization to endoplasmic reticulum |
| translational initiation |
| ribonucleoprotein complex |
| protein targeting to membrane |
| structural constituent of ribosome |
| heparin binding |
| nuclear-transcribed mRNA catabolic process |
| mRNA catabolic process |
| T cell activation |
| lymphocyte differentiation |
| RNA catabolic process |
| establishment of protein localization to membrane |
| leukocyte differentiation |
| glutamatergic synapse |
| regulation of translation |
| protein targeting |
| nucleobase-containing compound catabolic process |
| translation |
| lymphocyte activation |
| regulation of cellular amide metabolic process |
| peptide biosynthetic process |
| focal adhesion |
| establishment of protein localization to organelle |
| heterocycle catabolic process |
| cellular nitrogen compound catabolic process |
| modulation of chemical synaptic transmission |
| aromatic compound catabolic process |
| regulation of trans-synaptic signaling |
| protein localization to membrane |
| organic cyclic compound catabolic process |
| posttranscriptional regulation of gene expression |
| amide biosynthetic process |
| peptide metabolic process |
| hemopoiesis |
| hematopoietic or lymphoid organ development |
| immune system development |
| mRNA metabolic process |
| viral process |
| protein localization to organelle |
| symbiotic process |
| cellular amide metabolic process |
| interspecies interaction between organisms |
| cellular macromolecule catabolic process |
| leukocyte activation |
| intracellular protein transport |
| macromolecule catabolic process |
| cell activation |
| RNA binding |
| organonitrogen compound biosynthetic process |
| protein transport |
| intracellular transport |
| peptide transport |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| cellular nitrogen compound biosynthetic process |
| RNA metabolic process |
| cellular macromolecule biosynthetic process |
| negative regulation of gene expression |
| macromolecule biosynthetic process |
| organic substance catabolic process |
| cellular catabolic process |
| establishment of localization in cell |
| nitrogen compound transport |
| gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 1/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 1/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 3064
- Expression level (log2 read counts): 8.35
Expression Distribution
RPL22 Expression in NALM6 Cells: 8.35
