SCFD1
Gene Information
- Official Symbol: SCFD1
- Official Name: sec1 family domain containing 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 23256
- UniProt: Q8WVM8
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Sec1 |
GO Terms
| negative regulation of autophagosome assembly |
| regulation of ER to Golgi vesicle-mediated transport |
| Golgi-associated vesicle |
| negative regulation of macroautophagy |
| regulation of autophagosome assembly |
| negative regulation of organelle assembly |
| toxin transport |
| vesicle docking involved in exocytosis |
| regulation of vacuole organization |
| syntaxin binding |
| vesicle targeting, rough ER to cis-Golgi |
| vesicle docking |
| COPII vesicle coating |
| cis-Golgi network |
| vesicle coating |
| exocytic process |
| COPII-coated vesicle budding |
| vesicle targeting, to, from or within Golgi |
| Golgi vesicle budding |
| negative regulation of autophagy |
| retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum |
| vesicle targeting |
| Golgi cisterna membrane |
| vesicle budding from membrane |
| post-Golgi vesicle-mediated transport |
| protein N-terminus binding |
| organelle localization by membrane tethering |
| regulation of macroautophagy |
| establishment of vesicle localization |
| membrane docking |
| vesicle localization |
| endoplasmic reticulum to Golgi vesicle-mediated transport |
| regulation of organelle assembly |
| negative regulation of cellular catabolic process |
| protein-containing complex binding |
| vesicle organization |
| negative regulation of catabolic process |
| regulation of autophagy |
| response to hypoxia |
| regulation of intracellular transport |
| response to decreased oxygen levels |
| establishment of organelle localization |
| Golgi vesicle transport |
| negative regulation of organelle organization |
| response to oxygen levels |
| response to toxic substance |
| regulation of vesicle-mediated transport |
| organelle localization |
| negative regulation of cellular component organization |
| regulation of protein transport |
| cell morphogenesis |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| exocytosis |
| cellular component morphogenesis |
| regulation of cellular catabolic process |
| membrane organization |
| regulation of cellular localization |
| endoplasmic reticulum membrane |
| regulation of cellular component biogenesis |
| regulation of catabolic process |
| secretion by cell |
| regulation of protein localization |
| export from cell |
| secretion |
| response to abiotic stimulus |
| regulation of organelle organization |
| protein transport |
| intracellular transport |
| peptide transport |
| protein-containing complex assembly |
| amide transport |
| establishment of protein localization |
| establishment of localization in cell |
| nitrogen compound transport |
| protein-containing complex subunit organization |
| regulation of transport |
| vesicle-mediated transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 597/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 1/1 |
| bile duct | 23/28 |
| blood | 24/28 |
| bone | 22/26 |
| breast | 25/33 |
| central nervous system | 50/56 |
| cervix | 4/4 |
| colorectal | 13/17 |
| esophagus | 7/13 |
| fibroblast | 1/1 |
| gastric | 11/16 |
| kidney | 20/21 |
| liver | 14/20 |
| lung | 63/75 |
| lymphocyte | 12/16 |
| ovary | 21/26 |
| pancreas | 17/24 |
| peripheral nervous system | 15/16 |
| plasma cell | 14/15 |
| prostate | 1/1 |
| skin | 18/24 |
| soft tissue | 8/9 |
| thyroid | 2/2 |
| upper aerodigestive | 17/22 |
| urinary tract | 23/29 |
| uterus | 3/5 |
Essentiality in NALM6
- Essentiality Rank: 2109
- Expression level (log2 read counts): 5.54
Expression Distribution
SCFD1 Expression in NALM6 Cells: 5.54
