SCG2

• Official Symbol: SCG2
• Official Name: secretogranin II
• Aliases and Previous Symbols: N/A
• Entrez ID: 7857
• UniProt: P13521
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008].
• UniProt Summary: Secretogranin-2 is a neuroendocrine secretory granule protein, which is the precursor for biologically active peptides.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 6855
• Expression level (log2 read counts): -1.43

Expression Distribution

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SCG2 Expression in NALM6 Cells: -1.43