SLC10A1

Entrez Summary: N/A
UniProt Summary: The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

bile acid:sodium symporter activity
bile acid and bile salt transport
virus receptor activity
viral entry into host cell
entry into host cell
entry into host
monocarboxylic acid transport
organic hydroxy compound transport
sodium ion transport
interaction with host
basolateral plasma membrane
viral life cycle
organic acid transport
carboxylic acid transport
lipid transport
lipid localization
monovalent inorganic cation transport
organic anion transport
anion transport
metal ion transport
viral process
symbiotic process
interspecies interaction between organisms
cation transport
transmembrane transport
ion transport
integral component of plasma membrane