TRAPPC8

Entrez Summary: N/A
UniProt Summary: May be involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. {ECO:0000269|PubMed:21525244}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 630/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	28/28
blood	23/28
bone	25/26
breast	26/33
central nervous system	43/56
cervix	4/4
colorectal	15/17
esophagus	11/13
fibroblast	0/1
gastric	14/16
kidney	18/21
liver	17/20
lung	57/75
lymphocyte	15/16
ovary	24/26
pancreas	20/24
peripheral nervous system	15/16
plasma cell	13/15
prostate	1/1
skin	21/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	20/22
urinary tract	25/29
uterus	4/5

Expression Distribution

TRAPPIII protein complex
protein localization by the Cvt pathway
autophagy of peroxisome
protein localization to phagophore assembly site
TRAPP complex
phagophore assembly site
protein localization to vacuole
autophagosome assembly
autophagosome organization
vacuole organization
Golgi organization
macroautophagy
endoplasmic reticulum to Golgi vesicle-mediated transport
cytoplasmic vesicle
autophagy
process utilizing autophagic mechanism
Golgi vesicle transport
endomembrane system organization
protein localization to organelle
organelle assembly
intracellular transport
cellular protein localization
cellular macromolecule localization
cellular catabolic process
establishment of localization in cell
vesicle-mediated transport