CTNNBL1

Gene Information

Official Symbol: CTNNBL1
Official Name: catenin beta like 1
Aliases and Previous Symbols: N/A
Entrez ID: 56259
UniProt: Q8WYA6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
42°C R08 exp539	-2.59
BVD-523 15μM R02 exp67	-2.26
TIC10 10μM R08 exp532	-2.05
Brefeldin A 0.02μM R00 exp8	-2.03
UM131593 0.2μM R03 exp106	-1.85
Rotenone 2μM R00 exp33	-1.71
Arsenate 40μM R06 exp264	-1.7
Cycloheximide 0.02μM R00 exp14	1.71
QNZ 0.01μM R05 exp241	1.71
Bisphenol S 100μM R08 exp458	1.72
A-366 10μM R03 exp115	1.77
GSK626616 14μM R08 exp485	1.99
Dimethyl-Sulfoxide 1pc R03 exp120	2.05
Cytochalasin-B 5μM R07 exp349	2.29
Tozasertib 0.1μM R07 exp414	2.47
Deguelin 0.05μM R02 exp69	2.49
I-BRD9 4μM R07 exp365	2.85
Aminopterin 0.005μM R07 exp335	3.98

Gene	Correlation
CDK8	0.496
CKAP5	0.444
PDS5B	0.425
ARID4B	0.421
CWC22	0.417
PTMA	0.414
TSC2	0.414
C9orf78	0.412
PCGF1	0.408
E2F2	0.402

Global Fraction of Cell Lines Where Essential: 328/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	15/28
blood	17/28
bone	17/26
breast	15/33
central nervous system	32/56
cervix	0/4
colorectal	7/17
esophagus	5/13
fibroblast	1/1
gastric	4/16
kidney	9/21
liver	9/20
lung	42/75
lymphocyte	6/16
ovary	9/26
pancreas	11/24
peripheral nervous system	13/16
plasma cell	7/15
prostate	1/1
skin	11/24
soft tissue	3/9
thyroid	0/2
upper aerodigestive	3/22
urinary tract	6/29
uterus	1/5

Essentiality in NALM6

Essentiality Rank: 1443
Expression level (log2 read counts): 5.8

Expression Distribution