UBL5
Gene Information
- Official Symbol: UBL5
- Official Name: ubiquitin like 5
- Aliases and Previous Symbols: N/A
- Entrez ID: 59286
- UniProt: Q9BZL1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| ubiquitin |
GO Terms
| protein tag |
| positive regulation of protein targeting to mitochondrion |
| regulation of protein targeting to mitochondrion |
| positive regulation of establishment of protein localization to mitochondrion |
| regulation of establishment of protein localization to mitochondrion |
| regulation of protein targeting |
| positive regulation of mitochondrion organization |
| positive regulation of intracellular protein transport |
| regulation of mitochondrion organization |
| positive regulation of intracellular transport |
| regulation of intracellular protein transport |
| RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| mRNA splicing, via spliceosome |
| RNA splicing, via transesterification reactions |
| positive regulation of cellular protein localization |
| regulation of intracellular transport |
| RNA splicing |
| positive regulation of protein transport |
| positive regulation of establishment of protein localization |
| mRNA processing |
| regulation of cellular protein localization |
| positive regulation of organelle organization |
| mRNA metabolic process |
| regulation of protein transport |
| regulation of peptide transport |
| regulation of establishment of protein localization |
| RNA processing |
| regulation of cellular localization |
| positive regulation of transport |
| regulation of protein localization |
| positive regulation of cellular component organization |
| regulation of organelle organization |
| RNA metabolic process |
| regulation of transport |
| gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| BI-2536 0.02μM R03 exp96 | -1.79 |
| Pimelic-diphenylamide-106 0.5μM R00 exp27 | 1.88 |
Most Correlated Genes in Chemogenomics
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 731/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 1/1 |
| bile duct | 27/28 |
| blood | 28/28 |
| bone | 26/26 |
| breast | 33/33 |
| central nervous system | 56/56 |
| cervix | 4/4 |
| colorectal | 16/17 |
| esophagus | 13/13 |
| fibroblast | 1/1 |
| gastric | 16/16 |
| kidney | 19/21 |
| liver | 20/20 |
| lung | 74/75 |
| lymphocyte | 16/16 |
| ovary | 26/26 |
| pancreas | 23/24 |
| peripheral nervous system | 16/16 |
| plasma cell | 15/15 |
| prostate | 1/1 |
| skin | 24/24 |
| soft tissue | 8/9 |
| thyroid | 2/2 |
| upper aerodigestive | 22/22 |
| urinary tract | 28/29 |
| uterus | 5/5 |
Essentiality in NALM6
- Essentiality Rank: 297
- Expression level (log2 read counts): 6.2
Expression Distribution
UBL5 Expression in NALM6 Cells: 6.2
