BBS9

Entrez Summary: This gene is downregulated by parathyroid hormone in osteoblastic cells, and therefore is thought to be involved in parathyroid hormone action in bones. The exact function of this gene has not yet been determined. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan 2017].
UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Geldanamycin 0.015 to 0.025μM on day4 R07 exp316	-2.33
Pyronaridine 1μM R06 exp295	-2.31
Ixabepilone 0.004 to 0.005μM on day4 R04 exp184	-1.95
MSC2530818 10μM R07 exp379	-1.92
Geldanamycin 0.015 to 0.05μM on day4 R07 exp317	-1.9
Beta-Estradiol 0.55μM R07 exp425	-1.89
Calcium Ionophore 0.4μM R07 exp342	-1.87
THZ531 0.225μM R08 exp444	-1.84
Cabazitaxel 0.001μM R05 exp223	-1.76
Wortmannin 0.5μM R00 exp37	-1.76
UM131593 0.2μM R03 exp106	1.73
R-DABN 8μM R03 exp111	1.76
Resveratrol 16μM R03 exp147	1.78
DABN racemic mixture R03 exp93	1.79
Nifuroxazide 1μM R01 exp51	1.86
Rotenone 2μM R00 exp33	1.86
Zebularine 20μM R07 exp423	1.89
CyclicAMP 200μM R08 exp475	2.2
Nocodazole 0.2μM R00 exp24	2.29
Vinblastine 0.015μM R05 exp208	2.33
Nocodazole 0.1μM R03 exp94	3.1

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	1/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution