RNF111
Gene Information
- Official Symbol: RNF111
- Official Name: ring finger protein 111
- Aliases and Previous Symbols: N/A
- Entrez ID: 54778
- UniProt: Q6ZNA4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| zf-rbx1 |
| zf-C3HC4 |
GO Terms
| SUMO polymer binding |
| ubiquitin-dependent SMAD protein catabolic process |
| global genome nucleotide-excision repair |
| positive regulation of transforming growth factor beta receptor signaling pathway |
| positive regulation of cellular response to transforming growth factor beta stimulus |
| SMAD binding |
| PML body |
| positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
| nucleotide-excision repair |
| regulation of transforming growth factor beta receptor signaling pathway |
| positive regulation of protein ubiquitination |
| regulation of cellular response to transforming growth factor beta stimulus |
| positive regulation of protein modification by small protein conjugation or removal |
| transmembrane receptor protein serine/threonine kinase signaling pathway |
| regulation of protein ubiquitination |
| ubiquitin protein ligase activity |
| regulation of protein modification by small protein conjugation or removal |
| regulation of transmembrane receptor protein serine/threonine kinase signaling pathway |
| regulation of cellular response to growth factor stimulus |
| protein polyubiquitination |
| pattern specification process |
| DNA repair |
| ubiquitin-dependent protein catabolic process |
| modification-dependent protein catabolic process |
| modification-dependent macromolecule catabolic process |
| proteolysis involved in cellular protein catabolic process |
| protein-containing complex |
| cellular protein catabolic process |
| protein catabolic process |
| protein ubiquitination |
| enzyme linked receptor protein signaling pathway |
| DNA metabolic process |
| protein modification by small protein conjugation |
| cellular response to DNA damage stimulus |
| cellular macromolecule catabolic process |
| protein modification by small protein conjugation or removal |
| macromolecule catabolic process |
| organonitrogen compound catabolic process |
| positive regulation of transcription by RNA polymerase II |
| positive regulation of protein modification process |
| proteolysis |
| positive regulation of transcription, DNA-templated |
| positive regulation of cellular protein metabolic process |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| positive regulation of signal transduction |
| cellular response to stress |
| positive regulation of protein metabolic process |
| positive regulation of RNA metabolic process |
| organic substance catabolic process |
| cellular catabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of protein modification process |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 4102
- Expression level (log2 read counts): 5.67
Expression Distribution
RNF111 Expression in NALM6 Cells: 5.67
