CD52

Entrez Summary: N/A
UniProt Summary: May play a role in carrying and orienting carbohydrate, as well as having a more specific role.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
MK-1775 0.32μM R02 exp75	-2.51
Rapamycin 2μM plus FK-506 5μM R07 exp308	-1.86
Ethambutol 25μM R08 exp481	-1.81
Cidofovir 10μM R07 exp345	-1.77
Olaparib 4μM R08 exp512	-1.72
CVT-10216 0.1μM R06 exp278	1.75
LJH685 50μM R08 exp433	1.81
UNC2400 2μM R03 exp156	1.82
Vinblastine 0.2μM R03 exp108	1.96
SGC2043 10μM R03 exp152	2.02
PF-06409577 20μM R07 exp389	2.22
1-Methyl-nicotinamide-chloride 1000μM R03 exp113	2.29
Lead acetate 2000μM R08 exp497	2.32
Nicotinate 1000μM R03 exp140	2.4
NFN1 0.4μM R03 exp99	2.48

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

respiratory burst
sperm midpiece
intrinsic component of plasma membrane
anchored component of membrane
positive regulation of cytosolic calcium ion concentration
regulation of cytosolic calcium ion concentration
cellular calcium ion homeostasis
calcium ion homeostasis
cellular divalent inorganic cation homeostasis
divalent inorganic cation homeostasis
cellular metal ion homeostasis
metal ion homeostasis
cellular cation homeostasis
cellular ion homeostasis
cation homeostasis
inorganic ion homeostasis
cellular chemical homeostasis
ion homeostasis
cellular homeostasis
chemical homeostasis
homeostatic process
extracellular region
membrane