FARSB

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 739/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	28/28
blood	28/28
bone	26/26
breast	33/33
central nervous system	56/56
cervix	4/4
colorectal	17/17
esophagus	13/13
fibroblast	1/1
gastric	16/16
kidney	21/21
liver	20/20
lung	75/75
lymphocyte	16/16
ovary	26/26
pancreas	24/24
peripheral nervous system	16/16
plasma cell	15/15
prostate	1/1
skin	24/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	22/22
urinary tract	29/29
uterus	5/5

Expression Distribution

Gene	Correlation
HARS	0.574
ZNF259	0.436

phenylalanine-tRNA ligase complex
phenylalanyl-tRNA aminoacylation
phenylalanine-tRNA ligase activity
protein heterotetramerization
tRNA aminoacylation for protein translation
tRNA aminoacylation
amino acid activation
protein heterooligomerization
protein tetramerization
tRNA metabolic process
magnesium ion binding
cellular amino acid metabolic process
translation
peptide biosynthetic process
ncRNA metabolic process
protein complex oligomerization
amide biosynthetic process
peptide metabolic process
cellular amide metabolic process
carboxylic acid metabolic process
oxoacid metabolic process
organic acid metabolic process
RNA binding
organonitrogen compound biosynthetic process
ATP binding
protein-containing complex assembly
cellular nitrogen compound biosynthetic process
RNA metabolic process
cellular macromolecule biosynthetic process
small molecule metabolic process
macromolecule biosynthetic process
protein-containing complex subunit organization
membrane
gene expression