COG3

Entrez Summary: N/A
UniProt Summary: Involved in ER-Golgi transport. {ECO:0000269|PubMed:11929878}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 499/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	20/28
blood	16/28
bone	14/26
breast	17/33
central nervous system	33/56
cervix	3/4
colorectal	9/17
esophagus	9/13
fibroblast	1/1
gastric	11/16
kidney	21/21
liver	17/20
lung	52/75
lymphocyte	12/16
ovary	17/26
pancreas	19/24
peripheral nervous system	4/16
plasma cell	14/15
prostate	0/1
skin	19/24
soft tissue	8/9
thyroid	1/2
upper aerodigestive	16/22
urinary tract	23/29
uterus	4/5

Expression Distribution

Golgi transport complex
intra-Golgi vesicle-mediated transport
cis-Golgi network
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
trans-Golgi network membrane
Golgi cisterna membrane
Golgi organization
protein stabilization
endoplasmic reticulum to Golgi vesicle-mediated transport
protein glycosylation
macromolecule glycosylation
glycosylation
regulation of protein stability
glycoprotein biosynthetic process
Golgi vesicle transport
glycoprotein metabolic process
endomembrane system organization
Golgi membrane
carbohydrate derivative biosynthetic process
protein localization to organelle
Golgi apparatus
intracellular protein transport
carbohydrate derivative metabolic process
organonitrogen compound biosynthetic process
protein transport
intracellular transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
cellular macromolecule biosynthetic process
macromolecule biosynthetic process
establishment of localization in cell
nitrogen compound transport
vesicle-mediated transport