EIF2B5

• Official Symbol: EIF2B5
• Official Name: eukaryotic translation initiation factor 2B subunit epsilon
• Aliases and Previous Symbols: N/A
• Entrez ID: 8893
• UniProt: Q13144
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009].
• UniProt Summary: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 801
• Expression level (log2 read counts): 7.04

Expression Distribution

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EIF2B5 Expression in NALM6 Cells: 7.04