ESCO1

Official Symbol: ESCO1
Official Name: establishment of sister chromatid cohesion N-acetyltransferase 1
Aliases and Previous Symbols: N/A
Entrez ID: 114799
UniProt: Q5FWF5
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

post-translational protein acetylation
peptide-lysine-N-acetyltransferase activity
N-acetyltransferase activity
acetyltransferase activity
sister chromatid cohesion
regulation of DNA replication
chromatin
peptidyl-lysine acetylation
chromosome
sister chromatid segregation
protein acetylation
protein acylation
nuclear chromosome segregation
chromosome segregation
peptidyl-lysine modification
post-translational protein modification
zinc ion binding
peptidyl-amino acid modification
cell cycle process
chromosome organization
cell cycle