HOXA13
Gene Information
- Official Symbol: HOXA13
- Official Name: homeobox A13
- Aliases and Previous Symbols: N/A
- Entrez ID: 3209
- UniProt: P31271
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Expansion of a polyalanine tract in the encoded protein can cause hand-foot-uterus syndrome, also known as hand-foot-genital syndrome. [provided by RefSeq, Jul 2008].
- UniProt Summary: Sequence-specific, AT-rich binding transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior- posterior axis.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 12083
- Expression level (log2 read counts): -1.2
HOXA13 Expression in NALM6 Cells: -1.2
