NBPF12

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
I-BRD9 4μM R07 exp365	-2.3
Bortezomib 0.005μM R00 exp6	-2.19
Caffeine 2600μM R08 exp463	-2.16
BI-6727 0.001μM R01 exp42	-2.09
2-Methoxyestradiol 0.2μM R01 exp40	-1.83
CB-5083 0.4μM R08 exp468	-1.79
Hinokiflavone 12μM R08 exp487	-1.72
DKK1 89ng/ml R08 exp477	1.77
Rucaparib 6.5μM R08 exp520	1.83
UM0129480 7μM R02 exp85	1.83
Tanespimycin 14μM R08 exp527	1.89
DABN racemic mixture R03 exp93	2.13
Epigallocatechin gallate 20μM R05 exp230	2.21
Phenformin 20μM R05 exp212	2.27
HMS-I1 1μM R01 exp46	2.29

Global Fraction of Cell Lines Where Essential: 718/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	27/28
blood	28/28
bone	23/26
breast	32/33
central nervous system	53/56
cervix	4/4
colorectal	17/17
esophagus	13/13
fibroblast	1/1
gastric	15/16
kidney	21/21
liver	20/20
lung	73/75
lymphocyte	15/16
ovary	26/26
pancreas	24/24
peripheral nervous system	14/16
plasma cell	14/15
prostate	1/1
skin	24/24
soft tissue	9/9
thyroid	2/2
upper aerodigestive	21/22
urinary tract	29/29
uterus	5/5

Expression Distribution