SMIM15 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: SMIM15
Official Name: small integral membrane protein 15
Aliases and Previous Symbols: N/A
Entrez ID: 643155
UniProt: Q7Z3B0
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Bortezomib 0.005μM R00 exp6	-2.14
Chlorpromazine 10μM R07 exp344	1.72
Calcium Ionophore 0.4μM R07 exp342	1.74
MLN-4924 0.2μM R00 exp21	1.79
I-BRD9 4μM R07 exp365	1.83
Rifampicin 1μM R00 exp31	1.87
Wiskostatin 3μM R07 exp422	1.88
2-Methoxyestradiol 0.55μM R07 exp310	2.03
Senexin-A 25μM R07 exp400	2.06
Actinomycin-D 0.001μM R00 exp3	2.09
Pyridostatin 4μM R05 exp240	2.13
Vincristine 0.0005μM R04 exp190	2.14
Rifampicin 10μM R00 exp32	2.17
Oligomycin-A 20μM R00 exp26	2.31

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 3551
Expression level (log2 read counts): 5.43

Expression Distribution

Last modified: 2026/01/07 22:37
by 127.0.0.1