SRFBP1

Entrez Summary: N/A
UniProt Summary: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells (By similarity). {ECO:0000250|UniProtKB:Q9CZ91}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 342/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	13/28
blood	8/28
bone	14/26
breast	12/33
central nervous system	25/56
cervix	3/4
colorectal	4/17
esophagus	7/13
fibroblast	0/1
gastric	8/16
kidney	11/21
liver	8/20
lung	37/75
lymphocyte	6/16
ovary	14/26
pancreas	7/24
peripheral nervous system	7/16
plasma cell	3/15
prostate	0/1
skin	16/24
soft tissue	7/9
thyroid	1/2
upper aerodigestive	12/22
urinary tract	14/29
uterus	1/5

Expression Distribution

90S preribosome
maturation of SSU-rRNA
ribosomal small subunit biogenesis
rRNA processing
rRNA metabolic process
ribosome biogenesis
ncRNA processing
ribonucleoprotein complex biogenesis
ncRNA metabolic process
perinuclear region of cytoplasm
RNA processing
RNA binding
RNA metabolic process
gene expression