UBA6

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 3/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	1/28
blood	0/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	1/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

FAT10 activating enzyme activity
amygdala development
ubiquitin activating enzyme activity
dendritic spine development
hippocampus development
dendrite development
limbic system development
learning
pallium development
locomotory behavior
telencephalon development
learning or memory
cognition
forebrain development
ubiquitin-dependent protein catabolic process
modification-dependent protein catabolic process
modification-dependent macromolecule catabolic process
behavior
proteolysis involved in cellular protein catabolic process
cellular protein catabolic process
neuron projection development
protein catabolic process
protein ubiquitination
brain development
protein modification by small protein conjugation
head development
neuron development
cellular macromolecule catabolic process
central nervous system development
protein modification by small protein conjugation or removal
neuron differentiation
macromolecule catabolic process
organonitrogen compound catabolic process
plasma membrane bounded cell projection organization
cell projection organization
proteolysis
nervous system process
ATP binding
generation of neurons
neurogenesis