UQCRFS1

Gene Information
  • Official Symbol: UQCRFS1
  • Official Name: ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 7386
  • UniProt: P47985
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Cytochrome b-c1 complex subunit Rieske, mitochondrial: Component of the mitochondrial ubiquinol-cytochrome c reductase complex dimer (complex III dimer), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (PubMed:28673544). Incorporation of UQCRFS1 is the penultimate step in complex III assembly (By similarity). {ECO:0000250|UniProtKB:P47985, ECO:0000269|PubMed:28673544}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 811
  • Expression level (log2 read counts): 6.34

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1