RBM15
Gene Information
- Official Symbol: RBM15
- Official Name: RNA binding motif protein 15
- Aliases and Previous Symbols: N/A
- Entrez ID: 64783
- UniProt: Q96T37
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| RRM 1 |
| SPOC |
GO Terms
| thrombopoietin-mediated signaling pathway |
| RNA N6-methyladenosine methyltransferase complex |
| dosage compensation by inactivation of X chromosome |
| positive regulation of transcription of Notch receptor target |
| dosage compensation |
| branching involved in blood vessel morphogenesis |
| placenta blood vessel development |
| spleen development |
| ventricular septum morphogenesis |
| regulation of megakaryocyte differentiation |
| regulation of alternative mRNA splicing, via spliceosome |
| ventricular septum development |
| cardiac septum morphogenesis |
| negative regulation of myeloid cell differentiation |
| chemokine-mediated signaling pathway |
| RNA methylation |
| cellular response to chemokine |
| response to chemokine |
| regulation of mRNA splicing, via spliceosome |
| cardiac septum development |
| Notch signaling pathway |
| cardiac chamber morphogenesis |
| cardiac ventricle development |
| branching morphogenesis of an epithelial tube |
| regulation of RNA splicing |
| negative regulation of hemopoiesis |
| regulation of mRNA processing |
| placenta development |
| morphogenesis of a branching epithelium |
| mRNA binding |
| RNA modification |
| morphogenesis of a branching structure |
| cardiac chamber development |
| regulation of myeloid cell differentiation |
| regulation of gene expression, epigenetic |
| nuclear membrane |
| heart morphogenesis |
| macromolecule methylation |
| epithelial tube morphogenesis |
| methylation |
| angiogenesis |
| regulation of mRNA metabolic process |
| nuclear speck |
| blood vessel morphogenesis |
| reproductive structure development |
| reproductive system development |
| morphogenesis of an epithelium |
| negative regulation of immune system process |
| regulation of hemopoiesis |
| blood vessel development |
| vasculature development |
| cardiovascular system development |
| heart development |
| tissue morphogenesis |
| hematopoietic or lymphoid organ development |
| immune system development |
| tube morphogenesis |
| developmental process involved in reproduction |
| cytokine-mediated signaling pathway |
| viral process |
| negative regulation of cell differentiation |
| symbiotic process |
| interspecies interaction between organisms |
| tube development |
| circulatory system development |
| anatomical structure formation involved in morphogenesis |
| negative regulation of developmental process |
| animal organ morphogenesis |
| cellular response to cytokine stimulus |
| response to cytokine |
| epithelium development |
| negative regulation of transcription, DNA-templated |
| negative regulation of multicellular organismal process |
| positive regulation of transcription by RNA polymerase II |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| negative regulation of RNA metabolic process |
| negative regulation of cellular macromolecule biosynthetic process |
| RNA binding |
| reproductive process |
| reproduction |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| positive regulation of transcription, DNA-templated |
| negative regulation of biosynthetic process |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| regulation of immune system process |
| RNA metabolic process |
| negative regulation of gene expression |
| positive regulation of RNA metabolic process |
| tissue development |
| regulation of cell differentiation |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| KPNA4 | 0.412 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 4/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 1/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 1/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 1/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 17904
- Expression level (log2 read counts): 5.95
Expression Distribution
RBM15 Expression in NALM6 Cells: 5.95
